Which heart chamber has the thickest wall?

The left ventricle has the thickest wall of all heart chambers because it is responsible for pumping oxygenated blood to the entire body. This requires generating more force than the other chambers, particularly since it must overcome the greater resistance in the systemic circulation compared to the pulmonary circulation. The thick muscular walls enable the left ventricle to contract more powerfully, ensuring that blood is efficiently delivered to organs and tissues far from the heart.

In contrast, the other chambers do not need to exert as much force. For example, the right ventricle pumps blood to the lungs, which is a shorter distance and requires less muscular force. Similarly, the atria, including the right and left atria, are primarily involved in receiving blood and pushing it into the ventricles and do not require the same degree of muscular thickness as the ventricles that perform the heavy work of pumping blood throughout the body.